Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0G1UE
|
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| Former ID |
DIB018238
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| Drug Name |
[3H]AMPA
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [540671] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C7H10N2O4
|
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| InChI |
InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
|
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| InChIKey |
UUDAMDVQRQNNHZ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Glutamate receptor 4 | Target Info | Agonist | [543830] | |
| Glutamate receptor 1 | Target Info | Agonist | [543827] | ||
| Glutamate receptor 3 | Target Info | Modulator | [543829] | ||
| Glutamate receptor 2 | Target Info | Agonist | [543828] | ||
| KEGG Pathway | cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Circadian entrainment | |||||
| Retrograde endocannabinoid signaling | |||||
| Glutamatergic synapse | |||||
| Dopaminergic synapse | |||||
| Amphetamine addiction | |||||
| Nicotine addictionhsa04024:cAMP signaling pathway | |||||
| Long-term potentiation | |||||
| Long-term depression | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Nicotine addiction | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | EPHB forward signalingncadherinpathway:N-cadherin signaling events | ||||
| Reactome | Trafficking of AMPA receptors | ||||
| Trafficking of GluR2-containing AMPA receptors | |||||
| Unblocking of NMDA receptor, glutamate binding and activationR-HSA-204005:COPII (Coat Protein 2) Mediated Vesicle Transport | |||||
| Unblocking of NMDA receptor, glutamate binding and activation | |||||
| Cargo concentration in the ER | |||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellWP666:Hypothetical Network for Drug Addiction | |||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| BDNF signaling pathway | |||||
| References | |||||
| Ref 543827 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 444). | ||||
| Ref 543828 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 445). | ||||
| Ref 543829 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 446). | ||||
| Ref 543830 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 447). | ||||
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