Drug General Information
Drug ID
D0G2XN
Former ID
DIB014536
Drug Name
S-12968
Synonyms
Olradipine; Pranedipine; (-)-S 12968
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 3 [544583]
Company
Servier
Structure
Download
2D MOL

3D MOL

Formula
C26H34Cl2N2O12
Canonical SMILES
C1(=C(NC(=C([C@@H]1c1c(c(Cl)ccc1)Cl)C(=O)OCC)COCCOCCN)C<br />)C(=O)OC
CAS Number
CAS 132194-66-2
PubChem Compound ID
Target and Pathway
Target(s) Calcium channel Target Info Blocker [530048]
References
Ref 544583Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000221)
Ref 530048(+)-S-12967 and (-)-S-12968: 1,4-dihydropyridine stereoisomers with calcium channel agonistic and antagonistic properties in rat resistance arteries. Br J Pharmacol. 1991 Jul;103(3):1703-8.

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