Drug Information

Drug General Information
Drug ID
D0G4JI
Former ID
DAP000543
Drug Name
Pyruvic acid
Synonyms
BTS; Brenztraubensaeure; Acetylformic acid; Acide pyruvique; Pyroracemic acid; CH3COCOOH; A-Ketopropionic acid; Alpha-Ketopropionic acid; Alpha-Oxopropionsaeure; Alpha-keto propionic acid; Alpha-ketopropionic acid; P-9250; Pyruvic acid (8CI); Pyruvic acid (natural); Propanoic acid, 2-oxo-(9CI); 2-Ketopropionic acid; 2-Oxopropanoate; 2-Oxopropanoic acid; 2-Oxopropansaeure; 2-Oxopropionic acid; 2-Oxopropionsaeure; 2-oxo(1-14c)propanoic acid; 2-oxo-propionic acid
Drug Type
Small molecular drug
Indication Dietary shortage [ICD9: 260-269; ICD10:E40-E46] Approved [468040], [538216]
Therapeutic Class
Dietary supplement
Structure
Download
2D MOL

3D MOL
Formula
C3H4O3
InChI
InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKey
LCTONWCANYUPML-UHFFFAOYSA-N
CAS Number
CAS 127-17-3
PubChem Compound ID
1060
PubChem Substance ID
3324, 67115, 583760, 821307, 821314, 822632, 823091, 824014, 827046, 832413, 841522, 3134354, 5571669, 6436244, 7850314, 7890146, 8145308, 8150952, 10506205, 11447561, 11528430, 14716341, 14716592, 15194194, 17435687, 22387984, 22389510, 24439413, 24844228, 24846765, 24898862, 24901426, 24901427, 26702717, 26704720, 26707987, 26709793, 26710008, 26714555, 26714561, 29217748, 36487046, 38372743, 46505692, 46520143, 48414842, 49748488, 53789182, 56373996, 56373999
ChEBI ID
ChEBI:32816
Target and Pathway
Target(s) 4-aminobutyrate aminotransferase, mitochondrial Target Info Inhibitor [536555]
BioCyc Pathway GABA shunt
Valine degradation
Beta-alanine degradation
4-aminobutyrate degradation
KEGG Pathway Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine degradation
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
PANTHER Pathway Aminobutyrate degradation
Pyrimidine Metabolism
Gamma-aminobutyric acid synthesis
PathWhiz Pathway Aspartate Metabolism
Glutamate Metabolism
Beta-Alanine Metabolism
Valine, Leucine and Isoleucine Degradation
Propanoate Metabolism
WikiPathways GABA synthesis, release, reuptake and degradation
Alanine and aspartate metabolism
References
Ref 468040(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4809).
Ref 538216FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 065200.
Ref 536555DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

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