Drug Information

Drug General Information
Drug ID
D0G5QX
Former ID
DNC012928
Drug Name
TRIMEDOXIME
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527865]
Structure
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2D MOL

3D MOL
Formula
C15H18Br2N4O2
Canonical SMILES
C1=CN(C=CC1=C[NH+]=O)CCCN2C=CC(=C[NH+]=O)C=C2.[Br-].[Br<br />-]
InChI
1S/C15H16N4O2.2BrH/c20-16-12-14-2-8-18(9-3-14)6-1-7-19-10-4-15(5-11-19)13-17-21;;/h2-5,8-13H,1,6-7H2;2*1H
InChIKey
JHZHWVQTOXIXIV-UHFFFAOYSA-N
PubChem Compound ID
5359236
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [527865]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 527865Bioorg Med Chem Lett. 2006 Feb;16(3):622-7. Epub 2005 Nov 8.Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.
Ref 527865Bioorg Med Chem Lett. 2006 Feb;16(3):622-7. Epub 2005 Nov 8.Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

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