Drug Information
Drug General Information | |||||
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Drug ID |
D0G7MV
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Former ID |
DCL000544
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Drug Name |
INCB24360
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Drug Type |
Small molecular drug
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Company |
Incyte
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Structure |
Download2D MOL |
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Formula |
C9H7ClFN5O2
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InChI |
InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,13,15H,(H2,12,16)/b9-7+
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InChIKey |
MUVQOOPKPBEAJZ-VQHVLOKHSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Indoleamine 2,3-dioxygenase | Target Info | Inhibitor | [551022] | |
PathWhiz Pathway | Tryptophan Metabolism | ||||
Reactome | Tryptophan catabolism | ||||
References | |||||
Ref 524471 | ClinicalTrials.gov (NCT01961115) INCB024360 and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma. U.S. National Institutes of Health. | ||||
Ref 543000 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8221). |
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