Drug General Information
Drug ID
D0GF4I
Former ID
DIB018629
Drug Name
4-thio-UTP
Synonyms
4-S-UTP; 4-thiouridine triphosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539082]
Structure
Download
2D MOL
Formula
C9H15N2O14P3S
InChI
InChI=1S/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
InChIKey
GKVHYBAWZAYQDO-XVFCMESISA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) P2Y purinoceptor 2 Target Info Agonist [528028]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL5 Signaling Pathway
Reactome G alpha (q) signalling events
P2Y receptors
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 539082(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1730).
Ref 528028P2 receptors activated by uracil nucleotides--an update. Curr Med Chem. 2006;13(3):289-312.

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