Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0GQ1S
|
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| Former ID |
DIB019767
|
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| Drug Name |
DMCM
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C17H18N2O4
|
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| InChI |
InChI=1S/C17H18N2O4/c1-5-9-15-10-6-13(21-2)14(22-3)7-11(10)19-12(15)8-18-16(9)17(20)23-4/h6-8,19H,5H2,1-4H3
|
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| InChIKey |
GADIKQPUNWAMEB-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7979111, 10233718, 11111125, 14801123, 17405106, 26753583, 44434549, 47349350, 47646551, 47646552, 47795035, 47943750, 48018894, 48243352, 50034400, 50106334, 50106335, 50472779, 53777649, 57337961, 81065518, 85231027, 85788323, 92303958, 103181424, 103829635, 103960176, 104225368, 104373403, 117553242, 124749796, 124880001, 124880002, 127924665, 131342525, 135060476, 137008321, 137824683, 152036597, 162221496, 164776860, 178100998, 179235757, 198980730, 226789987, 241163626
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| Target and Pathway | |||||
| Target(s) | Gamma-aminobutyric-acid receptor alpha-2 subunit | Target Info | Modulator (allosteric modulator) | [2] | |
| Gamma-aminobutyric-acid receptor alpha-3 subunit | Target Info | Modulator (allosteric modulator) | [3] | ||
| Gamma-aminobutyric-acid receptor alpha-5 subunit | Target Info | Modulator (allosteric modulator) | [4] | ||
| GABA A receptor | Target Info | Modulator (allosteric modulator) | [5] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport | |||||
| GABA A receptor activation | |||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4179). | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 405). | ||||
| REF 3 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 406). | ||||
| REF 4 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 408). | ||||
| REF 5 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). | ||||
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