Drug General Information
Drug ID
D0GT4N
Former ID
DIB012575
Drug Name
BRL-55834
Drug Type
Small molecular drug
Indication Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] Discontinued in Phase 2 [544932]
Company
SmithKline Beecham plc
Structure
Download
2D MOL

3D MOL

Formula
C18H20F5NO3
Canonical SMILES
c12[C@@H](N3C(=O)CCCC3)[C@@H](C(Oc1ccc(C(C(F)(F)F)(F)F)<br />c2)(C)C)O
CAS Number
CAS 131899-25-7
PubChem Compound ID
Target and Pathway
Target(s) Potassium channel Target Info Opener [534028]
References
Ref 544932Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001581)
Ref 534028Comparison of the airways relaxant and hypotensive potencies of the potassium channel activators BRL 55834 and levcromakalim (BRL 38227) in vivo in guinea-pigs and rats. Br J Pharmacol. 1993 Aug;109(4):1133-9.

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