Drug General Information
Drug ID
D0H0BD
Former ID
DIB018417
Drug Name
[3H]strychnine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539499]
Structure
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2D MOL

3D MOL

Formula
C21H22N2O2
InChI
InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
InChIKey
QMGVPVSNSZLJIA-FVWCLLPLSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glycine Receptor (All subtypes) Target Info Antagonist [526747]
Glycine receptor Target Info Antagonist [543823]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Ligand-gated ion channel transport
WikiPathways Iron uptake and transport
References
Ref 539499(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2360).
Ref 526747Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron. 1992 Sep;9(3):491-6.
Ref 543823(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 425).

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