Drug Information
Drug General Information | |||||
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Drug ID |
D0H8OH
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Former ID |
DIB014142
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Drug Name |
Palovarotene
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Synonyms |
R-667; RG-667; Retinoid receptor agonist, Roche; Ro-3300074; Ro-330074
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Drug Type |
Small molecular drug
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Company |
Roche
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Structure |
Download2D MOL |
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Formula |
C27H30N2O2
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InChI |
InChI=1S/C27H30N2O2/c1-26(2)12-13-27(3,4)24-17-22(18-29-15-5-14-28-29)21(16-23(24)26)11-8-19-6-9-20(10-7-19)25(30)31/h5-11,14-17H,12-13,18H2,1-4H3,(H,30,31)/b11-8+
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InChIKey |
YTFHCXIPDIHOIA-DHZHZOJOSA-N
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CAS Number |
CAS 410528-02-8
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Retinoic acid receptor gamma | Target Info | Agonist | [531773] | |
References | |||||
Ref 531773 | Randomised controlled trial for emphysema with a selective agonist of the gamma-type retinoic acid receptor. Eur Respir J. 2012 Aug;40(2):306-12. | ||||
Ref 543031 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8276). |
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