Drug Information
Drug General Information | |||||
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Drug ID |
D0I1AC
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Former ID |
DNC007632
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Drug Name |
(4-chloro-1H-pyrazol-1-yl)(o-tolyl)methanone
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C11H9ClN2O
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Canonical SMILES |
CC1=CC=CC=C1C(=O)N2C=C(C=N2)Cl
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InChI |
1S/C11H9ClN2O/c1-8-4-2-3-5-10(8)11(15)14-7-9(12)6-13-14/h2-7H,1H3
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InChIKey |
LBFRMVGIANQWAQ-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Leukocyte elastase | Target Info | Inhibitor | [1] | |
KEGG Pathway | Transcriptional misregulation in cancer | ||||
Systemic lupus erythematosus | |||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
C-MYB transcription factor network | |||||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | ||||
Human Complement System | |||||
Degradation of collagen | |||||
References | |||||
REF 1 | J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase. | ||||
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