Drug Information

Drug General Information
Drug ID
D0I2EL
Former ID
DIB019478
Drug Name
compound 3j
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531413], [541073]
Structure
Download
2D MOL
Formula
C22H26FN5O5S
InChI
InChI=1S/C22H26FN5O5S/c1-22(2,3)33-21(29)27-9-7-14(8-10-27)32-20-16-12-26-28(19(16)24-13-25-20)18-6-5-15(11-17(18)23)34(4,30)31/h5-6,11-14H,7-10H2,1-4H3
InChIKey
FEAQKOJMPVAIBR-UHFFFAOYSA-N
PubChem Compound ID
53630394
PubChem Substance ID
127342881, 127342882, 127342883, 131286070, 131346382, 137218976, 139391997, 178102364, 223931672, 226719901, 247903719
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531413]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Ref 541073(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5738).
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.