TTD | Drug: D0I4FF

Drug General Information
Drug ID	D0I4FF
Former ID	DIB018531
Drug Name	20-hydroxy-LTB4
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540345]
Structure		Download 2D MOL
Formula	C20H32O5
InChI	InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25)/b5-4+,7-3-,13-8+,14-9-/t18-,19-/m1/s1
InChIKey	PTJFJXLGRSTECQ-PSPARDEHSA-N
PubChem Compound ID	5280745
PubChem Substance ID	7409, 801683, 4266084, 8143280, 8616382, 15002239, 24895660, 26754794, 39289786, 57357856, 77836670, 104046422, 113853910, 126524105, 135651386, 136351796, 137078321, 142970211, 179205546, 226509169, 242387352, 252371509, 252463282
Target and Pathway
Target(s)	Leukotriene B4 receptor 2	Target Info	Agonist	[534395]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Leukotriene receptors
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 540345	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3399).
Ref 534395	A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 1997 Jun 5;387(6633):620-4.

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Drug Information