Drug Information

Drug General Information
Drug ID
D0I6IU
Former ID
DIB007307
Drug Name
SC-41930
Synonyms
CGS-24115
Drug Type
Small molecular drug
Indication Inflammatory bowel disease [ICD9: 555, 556; ICD10:K50, K51] Discontinued in Phase 2 [541346], [544920]
Company
Intarcia Therapeutics.
Structure
Download
2D MOL

3D MOL
Formula
C28H36O7
InChI
InChI=1S/C28H36O7/c1-5-8-21-23(13-10-19-11-14-25(28(30)31)35-26(19)21)33-16-7-17-34-24-15-12-20(18(3)29)27(32-4)22(24)9-6-2/h10,12-13,15,25H,5-9,11,14,16-17H2,1-4H3,(H,30,31)
InChIKey
ZVVCSBSDFGYRCB-UHFFFAOYSA-N
CAS Number
CAS 120072-59-5
PubChem Compound ID
114999
PubChem Substance ID
10236589, 12014315, 14932652, 29296580, 50070437, 50071080, 53407382, 57338938, 85210640, 99222704, 103177985, 103916040, 104397364, 129962393, 134338773, 134341624, 135073323, 137174699, 142400984, 162379975, 162474333, 178102777, 228057561, 249792663
Target and Pathway
Target(s) Leukotriene B4 receptor 1 Target Info Modulator [526724]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 541346(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6156).
Ref 544920Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001549)
Ref 526724Multiple actions of the leukotriene B4 receptor antagonist SC-41930. J Pharmacol Exp Ther. 1992 Jan;260(1):187-91.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.