Drug Information
Drug General Information | |||||
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Drug ID |
D0I6WA
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Former ID |
DIB021048
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Drug Name |
THIIC
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [541416] | ||
Structure |
Download2D MOL |
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Formula |
C24H24F3N3O4
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InChI |
InChI=1S/C24H24F3N3O4/c1-14(2)21(31)17-8-9-19(20(22(17)32)24(25,26)27)34-12-16-6-4-15(5-7-16)10-28-23(33)18-11-30(3)13-29-18/h4-9,11,13-14,32H,10,12H2,1-3H3,(H,28,33)
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InChIKey |
RYINQFMHVVYWNS-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Metabotropic glutamate receptor 2 | Target Info | Modulator (allosteric modulator) | [531218] | |
References | |||||
Ref 531218 | N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes. J Pharmacol Exp Ther. 2011 Jan;336(1):165-77. |
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