Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I8BA
|
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| Former ID |
DNC006743
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| Drug Name |
1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528191] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H17NO2
|
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| Canonical SMILES |
C1C=CC(=O)C(N1C(=O)C2=CC=CC=C2)CC3=CC=CC=C3
|
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| InChI |
1S/C19H17NO2/c21-18-12-7-13-20(19(22)16-10-5-2-6-11-16)17(18)14-15-8-3-1-4-9-15/h1-12,17H,13-14H2
|
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| InChIKey |
CKNOOIXBZFVOCF-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Presenilin 2 | Target Info | Inhibitor | [528191] | |
| Presenilin 1 | Target Info | Inhibitor | [528191] | ||
| Gamma-secretase | Target Info | Inhibitor | [528191] | ||
| NetPath Pathway | Notch Signaling Pathway | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| NOTCH2 Activation and Transmission of Signal to the Nucleus | |||||
| EPH-ephrin mediated repulsion of cellsR-HSA-1474228:Degradation of the extracellular matrixR-HSA-1251985:Nuclear signaling by ERBB4 | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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