Drug General Information
Drug ID
D0J3QU
Former ID
DIB001817
Drug Name
ZD-7944
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [546304]
Company
Zeneca Group plc
Structure
Download
2D MOL

3D MOL

Formula
C31H34Cl2N2O2S
Canonical SMILES
C(=O)(N(C[C@H](c1cc(c(cc1)Cl)Cl)CCN1CCC(c2c(S(=O)C)cccc<br />2)CC1)C)c1ccccc1.Cl
CAS Number
CAS 161609-55-8
PubChem Compound ID
Target and Pathway
Target(s) NK-2 receptor Target Info Modulator [526161]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 546304Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007349)
Ref 526161Discovery of novel, orally active dual NK1/NK2 antagonists. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2769-73.

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