Drug General Information
Drug ID	D0J7NR
Former ID	DNC004192
Drug Name	5-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528087]
Structure		Download 2D MOL 3D MOL
Formula	C11H9N3O
Canonical SMILES	CC1=CC=CC2=CC3=C(NC(=O)N3)N=C12
InChI	1S/C11H9N3O/c1-6-3-2-4-7-5-8-10(13-9(6)7)14-11(15)12-8/h2-5H,1H3,(H2,12,13,14,15)
InChIKey	YZNZOJPHYDBVIZ-UHFFFAOYSA-N
PubChem Compound ID	15065143
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[528087]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

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