Drug Information

Drug General Information
Drug ID
D0K8TO
Former ID
DNCL002281
Drug Name
AP1903
Indication Transplant rejection [ICD9: 279.5, 996; ICD10:D89.8, T86] Phase 1/2 [524154]
Company
Bellicum Pharmaceuticals
Structure
Download
2D MOL
Formula
C78H98N4O20
PubChem Compound ID
16135625
Target and Pathway
Target(s) FK506-binding protein 1A Target Info Modulator [529386], [534700]
References
Ref 524154ClinicalTrials.gov (NCT01744223) Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant. U.S. National Institutes of Health.
Ref 529386Using gene transfer to circumvent off-target effects. Gene Ther. 2008 May;15(10):759-64.
Ref 534700Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10437-42.

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