Drug General Information
Drug ID	D0L2KO
Former ID	DNC003875
Drug Name	Azaphenylalanine derivative
Indication	Discovery agent		Investigative	[526986]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Coagulation factor Xa	Target Info	Inhibitor	[526986]
KEGG Pathway	Complement and coagulation cascades
PANTHER Pathway	Blood coagulation
Pathway Interaction Database	Beta2 integrin cell surface interactions
PathWhiz Pathway	Coagulation
Reactome	Extrinsic Pathway of Fibrin Clot Formation
	Intrinsic Pathway of Fibrin Clot Formation
	Common Pathway of Fibrin Clot Formation
	Gamma-carboxylation of protein precursors
	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
	Removal of aminoterminal propeptides from gamma-carboxylated proteins
WikiPathways	Complement and Coagulation Cascades
	Human Complement System
	PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
	Blood Clotting Cascade
	Formation of Fibrin Clot (Clotting Cascade)
References
Ref 526986	Bioorg Med Chem Lett. 2004 Mar 22;14(6):1563-7.Thrombin inhibitors built on an azaphenylalanine scaffold.
Ref 526986	Bioorg Med Chem Lett. 2004 Mar 22;14(6):1563-7.Thrombin inhibitors built on an azaphenylalanine scaffold.

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