TTD | Drug: D0L6MC

Drug General Information
Drug ID	D0L6MC
Former ID	DNC001287
Drug Name	SB 236057-A
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535363]
Structure		Download 2D MOL
Formula	C33H34N4O3
Canonical SMILES	CCN1CCC2(CC1)COC3=CC4=C(C=C23)N(CC4)C(=O)C5=CC=C(C=C5)C<br />6=C(C=C(C=C6)C7=NN=C(O7)C)C
InChI	1S/C33H34N4O3/c1-4-36-15-12-33(13-16-36)20-39-30-18-25-11-14-37(29(25)19-28(30)33)32(38)24-7-5-23(6-8-24)27-10-9-26(17-21(27)2)31-35-34-22(3)40-31/h5-10,17-19H,4,11-16,20H2,1-3H3
InChIKey	WXAKEEQOWUHGCI-UHFFFAOYSA-N
CAS Number	CAS 180083-49-2
PubChem Compound ID	5311426
PubChem Substance ID	7980572, 11056497, 14812141, 39341102, 53406949, 85209287, 114156064, 124954239, 124972114, 129646685, 134340493, 135650997, 225058099, 233400340
Target and Pathway
Target(s)	5-hydroxytryptamine 1B receptor	Target Info	Agonist	[535363]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 535363	SB-236057-A: a selective 5-HT1B receptor inverse agonist. CNS Drug Rev. 2001 Winter;7(4):433-44.
Ref 535363	SB-236057-A: a selective 5-HT1B receptor inverse agonist. CNS Drug Rev. 2001 Winter;7(4):433-44.

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Drug Information