Drug Information
Drug General Information | |||||
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Drug ID |
D0LJ1B
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Former ID |
DCL000955
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Drug Name |
Reparixin
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Synonyms |
Repertaxin; Reparixin [INN]; Reparixin (INN/USAN); (R)-2-(4-isobutylphenyl)propionylmethanesulfonamide; 2-(4-isobutylphenyl)propionylmethanesulfonamide
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Drug Type |
Small molecular drug
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Company |
Dompe s.p.a.
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Structure |
Download2D MOL |
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Formula |
C14H21NO3S
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InChI |
InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1
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InChIKey |
KQDRVXQXKZXMHP-LLVKDONJSA-N
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CAS Number |
CAS 266359-93-7
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | High affinity interleukin-8 receptor B | Target Info | Modulator | ||
High affinity interleukin-8 receptor A | Target Info | Modulator | |||
NetPath Pathway | TNFalpha Signaling PathwayNetPath_14:IL2 Signaling Pathway | ||||
Pathway Interaction Database | IL8- and CXCR2-mediated signaling eventsil8cxcr1_pathway:IL8- and CXCR1-mediated signaling events | ||||
References | |||||
Ref 537129 | New developments in immunosuppressive therapy for heart transplantation. Expert Opin Emerg Drugs. 2009 Mar;14(1):1-21. | ||||
Ref 543171 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8498). |
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