Drug Information

Drug General Information
Drug ID
D0LK7L
Former ID
DNC000567
Drug Name
Diphenylbutylpiperidines pimozide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535338]
Structure
Download
2D MOL

3D MOL
Formula
C18H20N6
Canonical SMILES
C1CN(CCN1CC2=CN=C(N2)C3=CC=CC=C3)C4=NC=CC=N4
InChI
1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22)
InChIKey
OTVQCHUIPJYASM-UHFFFAOYSA-N
CAS Number
CAS 178928-68-2
PubChem Compound ID
188942
PubChem Substance ID
7980118, 10260910, 14752667, 14801399, 33510547, 47954537, 48404542, 57396204, 79440170, 85209204, 103114526, 103318571, 103857974, 103952294, 113444874, 117522070, 126451647, 128861023, 134339350, 134339963, 135165781, 135650712, 136351236, 137074326, 137111890, 142282999, 143160218, 162805282, 163121853, 172876490, 178100334, 179293732, 204363639, 232578952, 233957622, 241376369, 246752231, 249617821, 252157171
Target and Pathway
Target(s) Voltage-dependent T-type calcium channel alpha-1G subunit Target Info Blocker [535338]
KEGG Pathway MAPK signaling pathway
Calcium signaling pathway
Circadian entrainment
Type II diabetes mellitus
PANTHER Pathway Endogenous cannabinoid signaling
GABA-B receptor II signaling
Nicotine pharmacodynamics pathway
Pathway Interaction Database Regulation of nuclear beta catenin signaling and target gene transcription
PathWhiz Pathway Muscle/Heart Contraction
Reactome NCAM1 interactions
WikiPathways NCAM signaling for neurite out-growth
Nicotine Activity on Chromaffin Cells
References
Ref 535338Differential inhibition of T-type calcium channels by neuroleptics. J Neurosci. 2002 Jan 15;22(2):396-403.
Ref 535338Differential inhibition of T-type calcium channels by neuroleptics. J Neurosci. 2002 Jan 15;22(2):396-403.

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