Drug General Information
Drug ID
D0LK8O
Former ID
DIB000860
Drug Name
LIFARIZINE HYDROCHLORIDE
Synonyms
BANM; Lifarizine hydrochloride < Rec INNM; RS-87476; 1-(Diphenylmethyl)-4-[5-methyl-2-(4-methylphenyl)-1H-imidazol-4-ylmethyl]piperazine trihydrochloride
Indication Nerve injury [ICD10:T14.4] Discontinued in Phase 2 [545611]
Structure
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2D MOL

3D MOL

Target and Pathway
Target(s) Calcium channel Target Info Blocker [534011], [551871]
References
Ref 545611Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003892)
Ref 534011The effect of lifarizine (RS-87476), a novel sodium and calcium channel modulator, on ischaemic dopamine depletion in the corpus striatum of the gerbil. Br J Pharmacol. 1993 May;109(1):175-7.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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