Drug Information
Drug General Information | |||||
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Drug ID |
D0M1FB
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Former ID |
DIB020566
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Drug Name |
N-palmitoylethanolamine
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Synonyms |
palmitoyl-EA; palmitamide MEA
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C18H37NO2
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InChI |
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
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InChIKey |
HXYVTAGFYLMHSO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
85235, 6752159, 7850592, 8152869, 11111603, 11113754, 11120210, 11120698, 11121186, 11121519, 11121999, 11147293, 11362588, 11365150, 11367712, 11370447, 11370448, 11373313, 11375874, 14825223, 17405463, 24278619, 26751935, 26751936, 26751937, 29223759, 47290911, 47662029, 47885184, 49661772, 49681174, 50064896, 50104611, 50104612, 50104613, 53778011, 56365485, 56463464, 57309612, 57322388, 77768141, 81054512, 85231178, 90341052, 91053556, 92304274, 92309870, 96025015, 99300784, 99302302
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Target and Pathway | |||||
Target(s) | Glucose-dependent insulinotropic receptor | Target Info | Agonist | [2] | |
G-protein coupled receptor 55 | Target Info | Agonist | [3] | ||
KEGG Pathway | cAMP signaling pathway | ||||
Insulin secretion | |||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling events | |||||
WikiPathways | Incretin Synthesis, Secretion, and InactivationWP1825:GPCR ligand binding | ||||
GPCR downstream signaling | |||||
GPCRs, Other | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3622). | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 126). | ||||
REF 3 | The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol. 2007 Dec;152(7):1092-101. Epub 2007 Sep 17. | ||||
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