Drug Information
Drug General Information | |||||
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Drug ID |
D0M6VK
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Former ID |
DAP001126
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Drug Name |
Methylscopolamine
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Synonyms |
Methscopolamine; Metylskopolamin; N-Methylscopolamine
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Drug Type |
Small molecular drug
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Indication | Peptic ulcer [ICD9: 531-534; ICD10:K25-K27] | Approved | [1], [2], [3] | ||
Therapeutic Class |
Anticholinergic Agents
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Structure |
Download2D MOL |
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Formula |
C18H24NO4+
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InChI |
InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1
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InChIKey |
LZCOQTDXKCNBEE-XJMZPCNVSA-N
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CAS Number |
CAS 155-41-9
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
SuperDrug ATC ID |
A03BB03
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SuperDrug CAS ID |
cas=013265106
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Target and Pathway | |||||
Target(s) | Muscarinic acetylcholine receptor M2 | Target Info | Antagonist | [4] | |
KEGG Pathway | Calcium signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
PI3K-Akt signaling pathway | |||||
Cholinergic synapse | |||||
Regulation of actin cytoskeleton | |||||
PANTHER Pathway | Alzheimer disease-amyloid secretase pathway | ||||
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||||
PathWhiz Pathway | Muscle/Heart Contraction | ||||
Reactome | Muscarinic acetylcholine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | |||||
Calcium Regulation in the Cardiac Cell | |||||
Regulation of Actin Cytoskeleton | |||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
GPCRs, Other | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 316). | ||||
REF 2 | Drug information of Methylscopolamine, 2008. eduDrugs. | ||||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
REF 4 | Methylacridinium and its Cholinergic Properties. Neurotox Res. 2009 Jun 30. | ||||
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