Drug Information

Drug General Information
Drug ID
D0M6VK
Former ID
DAP001126
Drug Name
Methylscopolamine
Synonyms
Methscopolamine; Metylskopolamin; N-Methylscopolamine
Drug Type
Small molecular drug
Indication Peptic ulcer [ICD9: 531-534; ICD10:K25-K27] Approved [540146], [550719], [551871]
Therapeutic Class
Anticholinergic Agents
Structure
Download
2D MOL

3D MOL
Formula
C18H24NO4+
InChI
InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1
InChIKey
LZCOQTDXKCNBEE-XJMZPCNVSA-N
CAS Number
CAS 155-41-9
PubChem Compound ID
71183
PubChem Substance ID
7849621, 43127561, 47289000, 50070602, 50071210, 57318056, 58602989, 77584265, 103070256, 103077998, 103509360, 104098623, 117554504, 135650725, 135651190, 135986195, 137249015, 162873644, 175267545, 179116781, 179520151, 223404203, 226446533, 242581383
SuperDrug ATC ID
A03BB03
SuperDrug CAS ID
cas=013265106
Target and Pathway
Target(s) Muscarinic acetylcholine receptor M2 Target Info Antagonist [537554]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Cholinergic synapse
Regulation of actin cytoskeleton
PANTHER Pathway Alzheimer disease-amyloid secretase pathway
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
PathWhiz Pathway Muscle/Heart Contraction
Reactome Muscarinic acetylcholine receptors
G alpha (i) signalling events
WikiPathways SIDS Susceptibility Pathways
Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
Regulation of Actin Cytoskeleton
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540146(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 316).
Ref 550719Drug information of Methylscopolamine, 2008. eduDrugs.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537554Methylacridinium and its Cholinergic Properties. Neurotox Res. 2009 Jun 30.

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