Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M7TW
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| Former ID |
DIB012289
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| Drug Name |
PF-3900422
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| Synonyms |
PF-03900422; Histamine H3 receptor antagonist (central nervous system disease), Pfizer
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| Indication | Central nervous system disease [ICD10:G00-G99] | Investigative | [1] | ||
| Company |
Pfizer Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C(=O)(c1cc(ccc1)c1cc2c(cc1)CC(CC2)N1CCCC1)N(C)CC
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| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | ||||
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