Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M8PM
|
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| Former ID |
DIB003356
|
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| Drug Name |
IRX-4
|
||||
| Synonyms |
IRX-2 + tumor-specific antigen (cancer), IRx Therapeutics
|
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| Indication | Prostate cancer [ICD9: 185; ICD10:C61] | Preclinical | [1] | ||
| Company |
IRX Therapeutics Inc
|
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| Target and Pathway | |||||
| Target(s) | Glutamate carboxypeptidase II | Target Info | Immunomodulator (Immunostimulant) | [2] | |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | ||||
| Metabolic pathways | |||||
| Vitamin digestion and absorption | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| TNFalpha Signaling Pathway | |||||
| Reactome | Amino acid synthesis and interconversion (transamination) | ||||
| WikiPathways | One Carbon Metabolism | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026363) | ||||
| REF 2 | Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development. Dev Dyn. 2014 Mar;243(3):381-92. | ||||
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