Drug Information
Drug General Information | |||||
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Drug ID |
D0MM2K
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Former ID |
DIB012054
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Drug Name |
CP-195543
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Synonyms |
LB4 antagonist (RA), Pfizer; LB4 antagonist (inflammation), Pfizer; Leukotriene B4 antagonist (inflammation), Pfizer; Leukotriene B4 antagonist (rheumatoid arthritis), Pfizer
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Drug Type |
Small molecular drug
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Company |
Pfizer Inc
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Structure |
Download2D MOL |
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Formula |
C24H19F3O4
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InChI |
InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
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InChIKey |
NZQDWKCNBOELAI-KSFYIVLOSA-N
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CAS Number |
CAS 204981-48-6
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Leukotriene B4 receptor 1 | Target Info | Antagonist | [530288] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
NetPath Pathway | IL4 Signaling Pathway | ||||
References | |||||
Ref 521954 | ClinicalTrials.gov (NCT00424294) A Study Of CP-195543 And Celecoxib Dual Therapy In Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health. | ||||
Ref 541345 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6155). |
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