Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0MM6A
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| Former ID |
DIB015110
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| Drug Name |
Coenzyme Q10 analog
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| Synonyms |
Coenzyme Q10 analog (mitochondrial disease); EPI-743; Coenzyme Q10 analog (mitochondrial disease), Edison Pharmaceuticals
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| Indication | Huntington's disease [ICD9: 294.1, 333.4; ICD10:F02.2, G10] | Phase 2 | [525079] | ||
| Company |
Edison Pharmaceuticals Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
CC(=CCC\\C(=C\\CC\\C(=C\\CC[C@@](C)(O)CCC1=C(C)C(=O)C(=<br />C(C)C1=O)C)\\C)\\C)C
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| InChI |
1S/C29H44O3/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8,32)19-17-26-25(7)27(30)23(5)24(6)28(26)31/h12,14,16,32H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
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| InChIKey |
LNOVHERIIMJMDG-XZXLULOTSA-N
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| Target and Pathway | |||||
| Target(s) | NAD(P)H dehydrogenase [quinone] 1 | Target Info | Modulator | [544447] | |
| KEGG Pathway | Ubiquinone and other terpenoid-quinone biosynthesis | ||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| Pathway Interaction Database | Validated transcriptional targets of TAp63 isoforms | ||||
| PathWhiz Pathway | Vitamin K Metabolism | ||||
| WikiPathways | Estrogen metabolism | ||||
| Oxidative Stress | |||||
| Transcriptional activation by NRF2 | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Aryl Hydrocarbon Receptor Pathway | |||||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | |||||
| Metabolism of amino acids and derivatives | |||||
| Aryl Hydrocarbon Receptor | |||||
| Dopamine metabolism | |||||
| Arylhydrocarbon receptor (AhR) signaling pathway | |||||
| References | |||||
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