Drug General Information
Drug ID
D0N1ZJ
Former ID
DNC010099
Drug Name
4-(tert-butylamino)naphthalen-1-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530623]
Structure
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2D MOL

3D MOL

Formula
C14H17NO
Canonical SMILES
CC(C)(C)NC1=CC=C(C2=CC=CC=C21)O
InChI
1S/C14H17NO/c1-14(2,3)15-12-8-9-13(16)11-7-5-4-6-10(11)12/h4-9,15-16H,1-3H3
InChIKey
YZPHFECVIINFFI-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Indoleamine 2,3-dioxygenase Target Info Inhibitor [530623]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation
L-kynurenine degradation
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
NAD de novo biosynthesis
KEGG Pathway Tryptophan metabolism
Metabolic pathways
African trypanosomiasis
NetPath Pathway TSLP Signaling Pathway
IL5 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Tryptophan Metabolism
Reactome Tryptophan catabolism
WikiPathways Tryptophan metabolism
Metabolism of amino acids and derivatives
References
Ref 530623J Med Chem. 2010 Feb 11;53(3):1172-89.Rational design of indoleamine 2,3-dioxygenase inhibitors.
Ref 530623J Med Chem. 2010 Feb 11;53(3):1172-89.Rational design of indoleamine 2,3-dioxygenase inhibitors.

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