Drug Information

Drug General Information
Drug ID
D0N5KS
Former ID
DCL000939
Drug Name
Pumosetrag
Synonyms
DDP-733; MKC-733; N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-oxo-4H-thieno[3,2-b]pyridine-6-carboxamide; N-((3R)-1-Azabicyclo(2.2.2)oct-3-yl)-7-oxo-4,7-dihydrothieno(3,2-b)pyridine-6-carboxamide; N-(1-azabicyclo[2.2.2]oct-8-yl)-2-oxo-9-thia-5-azabicyclo[4.3.0]nona-3,7,10-triene-3-carboxamide
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Phase 2 [536224]
Gastro-oesophageal reflux [ICD9: 530; ICD10:K21] Phase 1 [536224]
Company
Dynogen
Structure
Download
2D MOL

3D MOL
Formula
C15H17N3O2S
Canonical SMILES
C1CN2CCC1C(C2)NC(=O)C3=CNC4=C(C3=O)SC=C4
InChI
1S/C15H17N3O2S/c19-13-10(7-16-11-3-6-21-14(11)13)15(20)17-12-8-18-4-1-9(12)2-5-18/h3,6-7,9,12H,1-2,4-5,8H2,(H,16,19)(H,17,20)/t12-/m0/s1
InChIKey
AFUWQWYPPZFWCO-LBPRGKRZSA-N
CAS Number
CAS 194093-42-0
PubChem Compound ID
154104
PubChem Substance ID
14923065, 16110369, 23920531, 46230302, 56379272, 75489412, 104437997, 124961299, 125084540, 127400583, 134339381, 135261342, 135267501, 198950268, 226720111, 244467867
Target and Pathway
Target(s) 5-HT 3 receptor Target Info Modulator
References
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.