Drug General Information
Drug ID
D0N5UA
Former ID
DPR000037
Drug Name
Dianicline+rimonabant
Drug Type
Small molecular drug
Indication Tobacco dependence [ICD9: 305.1; ICD10:F17] Terminated [548622]
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL

Formula
C21H26ClN3O2
PubChem Compound ID
Target and Pathway
Target(s) Nicotinic acetylcholine receptor Target Info Agonist [537145]
Cannabinoid receptor 1 Target Info Agonist [537145]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 548622Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027143)
Ref 537145Emerging drugs for the treatment of tobacco dependence. Expert Opin Emerg Drugs. 2009 Mar;14(1):23-32.

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