TTD | Drug: D0N6QU

Drug General Information
Drug ID	D0N6QU
Former ID	DNC009467
Drug Name	2-hydroxygarveatin E
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528499]
Structure		Download 2D MOL 3D MOL
Formula	C20H20O6
Canonical SMILES	CCC1=C(C(=O)C2=CC3=C(C(=C2C1=O)O)C(=O)C(C(=O)C3(C)C)(C)<br />O)C
InChI	1S/C20H20O6/c1-6-9-8(2)14(21)10-7-11-13(16(23)12(10)15(9)22)17(24)20(5,26)18(25)19(11,3)4/h7,23,26H,6H2,1-5H3
InChIKey	MEDXQZJJCUKMBX-UHFFFAOYSA-N
PubChem Compound ID	16091656
Target and Pathway
Target(s)	Indoleamine 2,3-dioxygenase	Target Info	Inhibitor	[528499]
BioCyc Pathway	Superpathway of tryptophan utilization
	Tryptophan degradation
	L-kynurenine degradation
	Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
	NAD de novo biosynthesis
KEGG Pathway	Tryptophan metabolism
	Metabolic pathways
	African trypanosomiasis
NetPath Pathway	TSLP Signaling Pathway
	IL5 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Tryptophan Metabolism
Reactome	Tryptophan catabolism
WikiPathways	Tryptophan metabolism
WikiPathways	Metabolism of amino acids and derivatives
References
Ref 528499	J Nat Prod. 2006 Oct;69(10):1496-9.Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.
Ref 528499	J Nat Prod. 2006 Oct;69(10):1496-9.Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.

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Drug Information