Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N7HS
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| Former ID |
DIB000339
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| Drug Name |
ASP-3258
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| Synonyms |
PDE 4 inhibitor (airway inflammation), Astellas; Phosphodiesterase 4 inhibitor (airway inflammation), Astellas
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| Indication | Respiratory tract inflammation [ICD10:J00-J99] | Investigative | [543404] | ||
| Company |
Astellas Pharma Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1(c2c(n(c(=O)c1CCC(=O)O)CC)nc(cc2)C)c1cc(ccc1)Cl
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| Target and Pathway | |||||
| Target(s) | Type IV phosphodiesterase | Target Info | Inhibitor | [543406] | |
| CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [543404] | ||
| CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [543405] | ||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| PathWhiz Pathway | Purine Metabolism | ||||
| References | |||||
| Ref 543404 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300). | ||||
| Ref 543405 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1301). | ||||
| Ref 543406 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1303). | ||||
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