Drug General Information
Drug ID	D0N7HY
Former ID	DIB020623
Drug Name	Org 12962
Synonyms	Org-12962; Org12962
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539054]
Structure		Download 2D MOL
Formula	C10H11ClF3N3
InChI	InChI=1S/C10H11ClF3N3/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17/h1-2,15H,3-6H2
InChIKey	QZYYPQAYSFBKPW-UHFFFAOYSA-N
PubChem Compound ID	9796408
PubChem Substance ID	14848193, 24106295, 44832418, 50076970, 78818513, 85212004, 93816413, 103604038, 109620386, 124758392, 125432844, 126732500, 129099331, 134480425, 135580112, 135650777, 136351633, 137000416, 137144107, 139711519, 143471802, 160822611, 162049884, 162118603, 162301771, 162473604, 163382414, 165816001, 174546216, 187576417, 203092652, 223595679, 223657866, 227172108, 250203462, 252493275
Target and Pathway
Target(s)	5-hydroxytryptamine 2C receptor	Target Info	Agonist	[527178]
	5-hydroxytryptamine 2A receptor	Target Info	Agonist	[527178]
	5-hydroxytryptamine 2B receptor	Target Info	Agonist	[527178]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channelshsa04020:Calcium signaling pathway
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathwayP04374:5HT2 type receptor mediated signaling pathwayP04374:5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling eventsR-HSA-390666:Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signalingWP733:Serotonin Receptor 2 and STAT3 Signaling
	SIDS Susceptibility Pathways
	GPCR downstream signaling
	GPCRs, OtherWP732:Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
References
Ref 539054	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 170).
Ref 527178	Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):114-23. Epub 2004 Jul 30.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.