Drug Information

Drug General Information
Drug ID
D0N8XL
Former ID
DIB012523
Drug Name
BMS-605339
Synonyms
NS3 protease inhibitor (hepatitis C virus infection), BMS
Indication HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] Terminated [548960]
Company
Bristol-Myers Squibb Co
Structure
Download
2D MOL

3D MOL
Canonical SMILES
[C@@H]1(C=C)C[C@@]1(C(=O)NS(=O)(=O)C1CC1)NC(=O)[C@@H]1C<br />[C@H](CN1C(=O)[C@H](C(C)(C)C)NC(=O)OC(C)(C)C)Oc1c2ccc(c<br />c2ccn1)OC
Target and Pathway
Target(s) Nonstructural protein NS3 Target Info Inhibitor [532678]
References
Ref 548960Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030836)
Ref 532678Discovery and early clinical evaluation of BMS-605339, a potent and orally efficacious tripeptidic acylsulfonamide NS3 protease inhibitor for the treatment of hepatitis C virus infection. J Med Chem.2014 Mar 13;57(5):1708-29.

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