Drug Information

Drug General Information
Drug ID
D0O0AO
Former ID
DNC000372
Drug Name
Bzurea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535400]
Structure
Download
2D MOL

3D MOL
Formula
C15H19Cl2N3O4
Canonical SMILES
CC(C)NC1=NC2=CC(=C(C=C2N1C3C(C(C(O3)CO)O)O)Cl)Cl
InChI
1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1
InChIKey
KJFBVJALEQWJBS-XUXIUFHCSA-N
CAS Number
CAS 176161-24-3
PubChem Compound ID
471161
PubChem Substance ID
626300, 10306757, 12015036, 14804326, 14853350, 47206634, 50521885, 57405610, 71821537, 93302821, 103651231, 103842355, 109755304, 117368779, 118047322, 126629454, 128390115, 134339815, 134340205, 135078600, 137263772, 137267657, 142220709, 152101613, 160839470, 163099359, 163402541, 164824892, 184528158, 184546347, 198936541, 204433727, 210275491, 210281139, 223554910, 225069495, 227071991, 252345516, 252511550
SuperDrug ATC ID
J05AF06
SuperDrug CAS ID
cas=136470785
Target and Pathway
Target(s) Glycogen phosphorylase, muscle form Target Info Inhibitor [535400]
BioCyc Pathway Glycogenolysis
KEGG Pathway Starch and sucrose metabolism
Metabolic pathways
Insulin signaling pathway
Glucagon signaling pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
WikiPathways Glycogen Metabolism
Metabolism of carbohydrates
References
Ref 535400Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies. Eur J Biochem. 2002 Mar;269(6):1684-96.
Ref 535400Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies. Eur J Biochem. 2002 Mar;269(6):1684-96.

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