Drug Information

Drug General Information
Drug ID
D0O0HR
Former ID
DIB020131
Drug Name
KF 17837S
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467617]
Structure
Download
2D MOL
Formula
C20H26N4O4
InChI
InChI=1S/C20H26N4O4/c1-6-10-23-18-16(19(25)24(11-7-2)20(23)26)22(3)17(21-18)13-8-9-14(27-4)15(12-13)28-5/h8-9,12H,6-7,10-11H2,1-5H3
InChIKey
FSUNYKAEJIVAHY-UHFFFAOYSA-N
PubChem Compound ID
123739
PubChem Substance ID
24506177, 29303944, 50915529, 57340556, 85209811, 104419206, 126435307, 134224007, 135078961, 135650455, 160833623, 163096176, 163396170, 163843573, 189659109, 223562298, 252503372
Target and Pathway
Target(s) Adenosine A2b receptor Target Info Antagonist [534396]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Alcoholism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
Reactome Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 467617(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 428).
Ref 534396Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. Br J Pharmacol. 1997 Jun;121(3):353-60.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.