Drug Information

Drug General Information
Drug ID
D0O2WB
Former ID
DAP000809
Drug Name
Pyridostigmine
Synonyms
Pyridostigminum; Regonol; Pyridostigmine Bromine; Mestinon (TN); Mestinon-SR; Regonol (TN); AQ-776/42801589; Pyridinium, 3-hydroxy-1-methyl-, dimethylcarbamate (ester); Pyridinium, 3-(((dimethylamino)carbonyl)oxy)-1-methyl-(9CI); (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate; 1-methyl-3-pyridiniumyl dimethylcarbamate; 3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium
Drug Type
Small molecular drug
Indication Myasthenia gravis [ICD9: 358; ICD10:G70.0] Approved [538182]
Therapeutic Class
Parasympathomimetics
Company
Valeant Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C9H13N2O2+
Canonical SMILES
C[N+]1=CC=CC(=C1)OC(=O)N(C)C
InChI
1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1
InChIKey
RVOLLAQWKVFTGE-UHFFFAOYSA-N
CAS Number
CAS 155-97-5
PubChem Compound ID
4991
PubChem Substance ID
9614, 866421, 4892591, 7437582, 7980440, 8153073, 11111694, 11335382, 11360621, 11364497, 11367059, 11369621, 11373077, 11377783, 11432882, 11461593, 11484637, 11488677, 11491724, 11495417, 15171335, 17153897, 29224064, 46506129, 47440132, 47662142, 47959602, 48334363, 50033601, 50100334, 50104217, 50361105, 90340824, 93166542, 95512043, 103310147, 103853547, 104147440, 104307965, 124750185, 124881247, 124881248, 124881249, 129188084, 134338090, 134974263, 137005304, 138967994, 140053019, 143458650
SuperDrug ATC ID
N07AA02
SuperDrug CAS ID
cas=000155975
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [537124]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 538182FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040457.
Ref 537124Neuromuscular blockade, reversal agent use, and operating room time: retrospective analysis of US inpatient surgeries. Curr Med Res Opin. 2009 Apr;25(4):943-50.

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