Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O3NG
|
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| Former ID |
DNC000564
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| Drug Name |
Dimaprit
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C6H15N3S
|
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| InChI |
InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)
|
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| InChIKey |
OLHQOJYVQUNWPL-UHFFFAOYSA-N
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| CAS Number |
CAS 60-00-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5021259, 7979095, 8151956, 11112685, 11113535, 11467011, 11468131, 11486682, 15265190, 16961065, 26751746, 29222222, 47365385, 47662484, 47959949, 48334687, 49699373, 49846697, 49900669, 50901984, 56314095, 57309579, 57321594, 85209056, 85788602, 91567534, 95509074, 96024151, 103124474, 103173420, 104302459, 117373937, 124882517, 124882518, 128825496, 132562708, 134339961, 135008316, 135650186, 137041679, 143456392, 162221383, 162890531, 179236213, 198949187, 221672748, 223446363, 226710935
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| ChEBI ID |
ChEBI:42191
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| Target and Pathway | |||||
| Target(s) | Histamine H2 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretion | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Histamine H2 receptor mediated signaling pathway | |||||
| PathWhiz Pathway | Intracellular Signalling Through Histamine H2 Receptor and Histamine | ||||
| Gastric Acid Production | |||||
| Reactome | Histamine receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1248). | ||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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