Drug General Information
Drug ID	D0O4IO
Former ID	DIB021263
Drug Name	ztz240
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[1]
Structure		Download 2D MOL
Formula	C12H8ClFN2O
InChI	InChI=1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)
InChIKey	URPKVELJRWKNQS-UHFFFAOYSA-N
PubChem Compound ID	3780776
PubChem Substance ID	5355977, 9969713, 12219452, 14774327, 25820757, 41631344, 53753202, 87350301, 87457387, 112185532, 125440713, 131564907, 138984601, 160687872, 165815419, 187563319, 196377600, 223366003, 231067715, 243151369, 252643828
Target and Pathway
Target(s)	Potassium voltage-gated channel subfamily KQT member 2	Target Info	Activator	[2]
KEGG Pathway	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Reactome	Voltage gated Potassium channels
	Interaction between L1 and Ankyrins
WikiPathways	Potassium Channels
	L1CAM interactions
References
REF 1	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7668).
REF 2	Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions. J Biol Chem. 2010 Sep 3;285(36):28322-32.

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