Drug General Information
Drug ID	D0O5GK
Former ID	DNCL001979
Drug Name	R-phenserine
Synonyms	Posiphen (TN)
Indication	Alzheimer disease; Mild cognitive impairment [ICD9: 331.0, 331.83; ICD10:F06.7, G30, G31.84]		Phase 2	[548049]
Company	QR Pharma
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Acetylcholinesterase	Target Info	Inhibitor	[527603]
KEGG Pathway	Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer Pathway
References
Ref 548049	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021506)
Ref 527603	An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease. Curr Alzheimer Res. 2005 Jul;2(3):281-90.

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