Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O7NV
|
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| Former ID |
DIB013171
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| Drug Name |
DOV-51892
|
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| Synonyms |
DOV-22047; GABA-A modulators, DOV
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| Indication | Panic disorder [ICD9: 300.01, 300.21; ICD10:F41.0] | Investigative | [1] | ||
| Company |
DOV Pharmaceutical Inc
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C(=O)(c1c2nccc(n2nc1)c1cc(ncc1)Cl)c1ccccn1
|
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| Target and Pathway | |||||
| Target(s) | GABA A receptor | Target Info | Modulator | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activation | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). | ||||
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