Drug General Information
Drug ID	D0O8YZ
Former ID	DNC011297
Drug Name	NSC-65069
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531262]
Structure		Download 2D MOL 3D MOL
Formula	C12H10O5
Canonical SMILES	C1=C(C=C(C=C1O)O)C2=C(C=C(C=C2O)O)O
InChI	1S/C12H10O5/c13-7-1-6(2-8(14)3-7)12-10(16)4-9(15)5-11(12)17/h1-5,13-17H
InChIKey	KICYRZIVKKYRFS-UHFFFAOYSA-N
PubChem Compound ID	248349
Target and Pathway
Target(s)	NAD(P)H dehydrogenase [quinone] 1	Target Info	Inhibitor	[531262]
KEGG Pathway	Ubiquinone and other terpenoid-quinone biosynthesis
NetPath Pathway	TCR Signaling Pathway
Pathway Interaction Database	Validated transcriptional targets of TAp63 isoforms
PathWhiz Pathway	Vitamin K Metabolism
WikiPathways	Estrogen metabolism
	Oxidative Stress
	Transcriptional activation by NRF2
	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Aryl Hydrocarbon Receptor Pathway
	Apoptosis-related network due to altered Notch3 in ovarian cancer
	Metabolism of amino acids and derivatives
	Aryl Hydrocarbon Receptor
	Dopamine metabolism
	Arylhydrocarbon receptor (AhR) signaling pathway
References
Ref 531262	Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262	Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

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