Drug Information
Drug General Information | |||||
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Drug ID |
D0O9XN
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Former ID |
DIB006258
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Drug Name |
APD-597
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Synonyms |
JNJ-38431055
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Drug Type |
Small molecular drug
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Company |
Arena Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Formula |
C21H29N5O6S
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InChI |
InChI=1S/C21H29N5O6S/c1-13(2)31-21(27)26-10-8-15(9-11-26)32-20-18(30-4)19(22-12-23-20)25-16-6-7-17(24-14(16)3)33(5,28)29/h6-7,12-13,15H,8-11H2,1-5H3,(H,22,23,25)
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InChIKey |
WPDCHTSXOPUOII-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Glucose-dependent insulinotropic receptor | Target Info | Agonist | [531766] | |
KEGG Pathway | cAMP signaling pathway | ||||
Insulin secretion | |||||
WikiPathways | Incretin Synthesis, Secretion, and Inactivation | ||||
References | |||||
Ref 522679 | ClinicalTrials.gov (NCT00910923) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-38431055 in Healthy Male Volunteers. U.S. National Institutes of Health. | ||||
Ref 541062 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5727). |
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