Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0OP7B
|
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| Former ID |
DIB002106
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| Drug Name |
LY-210073
|
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Company |
Eli Lilly & Co
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| Structure |
|
Download2D MOL |
|||
| Formula |
C30H28O8
|
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| Canonical SMILES |
c12c(c(=O)c3c(o1)ccc(c3)C(=O)O)ccc(c2CCC(=O)O)OCCCC/C=C<br />/c1ccc(cc1)OC
|
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| CAS Number |
CAS 148291-65-0
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Leukotriene B4 receptor 1 | Target Info | Modulator | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| Reactome | Leukotriene receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Nucleotide GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Spinal Cord Injury | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34. | ||||
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