Drug Information
Drug General Information | |||||
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Drug ID |
D0OT9B
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Former ID |
DIB020191
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Drug Name |
L-aspartic acid
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Synonyms |
L-Asp; L-aspartate; Aspatofort
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540269] | ||
Structure |
Download2D MOL |
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Formula |
C4H7NO4
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InChI |
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
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InChIKey |
CKLJMWTZIZZHCS-REOHCLBHSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
3351, 627127, 820598, 820604, 821992, 823680, 824125, 827788, 830716, 841716, 7847081, 7885984, 8025800, 8144794, 8153703, 10318344, 10527673, 11109886, 11113409, 14710666, 15119963, 17404696, 24277948, 24698176, 24769862, 24770212, 24847046, 24890873, 24890976, 24891191, 24891385, 24902272, 26702710, 26705516, 26712266, 26712700, 26718511, 26751648, 29224983, 46507997, 47217068, 47365467, 47811039, 47960025, 48334792, 48415581, 48419498, 49746800, 49829767, 49856449
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Target and Pathway | |||||
Target(s) | Glutamate [NMDA] receptor subunit epsilon 1 | Target Info | Agonist | [543837] | |
Glutamate [NMDA] receptor subunit epsilon 2 | Target Info | Agonist | [543838] | ||
NMDA receptor subunit NR1 | Target Info | Agonist | [543836] | ||
GluN2D | Target Info | Agonist | [543840] | ||
GluN2C | Target Info | Agonist | [543839] | ||
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
Calcium signaling pathway | |||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Circadian entrainment | |||||
Long-term potentiation | |||||
Glutamatergic synapse | |||||
Dopaminergic synapse | |||||
Alzheimer's disease | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
Cocaine addiction | |||||
Amphetamine addiction | |||||
Nicotine addiction | |||||
Alcoholism | |||||
Systemic lupus erythematosushsa04014:Ras signaling pathway | |||||
Huntington's disease | |||||
PANTHER Pathway | Huntington disease | ||||
Ionotropic glutamate receptor pathway | |||||
Metabotropic glutamate receptor group III pathway | |||||
Metabotropic glutamate receptor group I pathway | |||||
Muscarinic acetylcholine receptor 1 and 3 signaling pathwayP00029:Huntington disease | |||||
Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||||
Pathway Interaction Database | Reelin signaling pathwayerbb4_pathway:ErbB4 signaling events | ||||
Reelin signaling pathway | |||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
Alzheimers DiseaseWP666:Hypothetical Network for Drug Addiction | |||||
BDNF signaling pathwayWP706:SIDS Susceptibility Pathways | |||||
Spinal Cord Injury | |||||
BDNF signaling pathway | |||||
Alzheimers Disease | |||||
References | |||||
Ref 543836 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 455). | ||||
Ref 543837 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 456). | ||||
Ref 543838 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 457). | ||||
Ref 543839 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 458). | ||||
Ref 543840 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 459). |
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