Drug General Information
Drug ID
D0P1QW
Former ID
DCL000715
Drug Name
Becampanel
Synonyms
AMP397; AMP-397; AMP-397A; [(7-nitro-2,3-dioxo-1,4-dihydroquinoxalin-5-yl)methylamino]methylphosphonic acid
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Discontinued in Phase 2 [536498]
Company
Novartis
Structure
Download
2D MOL

3D MOL

Formula
C10H11N4O7P
Canonical SMILES
C1=C(C=C(C2=C1NC(=O)C(=O)N2)CNCP(=O)(O)O)[N+](=O)[O-]
InChI
1S/C10H11N4O7P/c15-9-10(16)13-8-5(3-11-4-22(19,20)21)1-6(14(17)18)2-7(8)12-9/h1-2,11H,3-4H2,(H,12,15)(H,13,16)(H2,19,20,21)
InChIKey
ABFMMCZFKUIJGQ-UHFFFAOYSA-N
CAS Number
CAS 188696-80-2
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [536166], [536498]
References
Ref 536498Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.
Ref 536166Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17.
Ref 536498Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.

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