Drug General Information
Drug ID	D0P3ND
Former ID	DNC010800
Drug Name	1-[(7-Fluoronaphth-2-yl)methyl]-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530867]
Structure		Download 2D MOL 3D MOL
Formula	C14H11FN2
Canonical SMILES	C1=CC(=CC2=C1C=CC(=C2)F)CN3C=CN=C3
InChI	1S/C14H11FN2/c15-14-4-3-12-2-1-11(7-13(12)8-14)9-17-6-5-16-10-17/h1-8,10H,9H2
InChIKey	SFBANCVOUQRQEX-UHFFFAOYSA-N
PubChem Compound ID	46887506
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[530867]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 530867	Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. Epub 2010 Apr 8.Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Ref 530867	Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. Epub 2010 Apr 8.Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.